Condition - PCOS, Irregular Cycles, Male Factor (Motility Issues)
A couple, aged 32 and 36, had been trying to conceive for three years when they were confronted with devastating news. The husband was diagnosed with azoospermia, meaning no sperm were found in his semen analysis. They were advised to consider a donor sperm program, a suggestion that can be heartbreaking for anyone hoping for a genetic child.
Over the years, they tried multiple treatments, including Ayurvedic, Unani, and hormonal therapies, but none yielded results. Their hope of having a child of their own seemed to be slipping away.
When they came to us, we decided to reset their fertility journey with a comprehensive and individualized plan. The husband, weighing 104 kilograms, was enrolled in an intensive weight loss program to improve overall health and sperm production. He also started on empirical recombinant hormone injections to stimulate spermatogenesis.
For the wife, we planned an IVF stimulation protocol while preparing for micro-TESE (microdissection testicular sperm extraction) for the husband. These combined efforts allowed us to finally obtain viable sperm and create embryos.
The first embryo transfer did not result in pregnancy, but we did not lose hope. To improve implantation chances, we performed an Endometrial Receptivity Assay and planned a personalized embryo transfer based on her natural cycle.
The second transfer was successful. The couple conceived twins, and although they were delivered preterm, both a boy and a girl are now thriving and growing into lovely toddlers. This success highlights that male infertility can be addressed effectively with a combination of advanced interventions and lifestyle optimization.
Andrology, the field dedicated to male infertility, requires highly individualized care. Options such as testicular PRP, stem cell therapy, TESA, and micro-TESE, when combined with weight management, lifestyle changes, and medical optimization, can turn previously hopeless situations into joyful outcomes.
This story emphasizes the importance of patience, tailored treatment, and hope. For couples struggling with male factor infertility, personalized approaches and persistence can truly make parenthood possible.
“Dreaming of a genetic child? Start your personalized fertility journey today
Schedule a consultation with Dr. Nasrin Hasan to discuss a personalised fertility treatment plan.